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A recent randomized, placebo-controlled, phase 3 study conducted by Elkind-Hirsch et al

The gastrointestinal side effects common with GLP-1 receptor agonistsincluding nausea, diarrhea, constipation, and abdominal discomfortmay overlap with or potentially exacerbate symptoms related to altered bile flow after cholecystectomy

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First injection: moderate redness, itching, 48 to 72 hours Second injection: mild redness, minimal itching, 24 to 48 hours Third injection: barely noticeable or absent Long-term outcome: reactions resolve completely by week 6 to 8 Pattern 2: Stable mild severity (20% of patients)

diabetic patients should monitor their blood glucose levels closely