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Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: A suggested solution based on in vivo occupancy

This fundamental difference in treatment duration shapes the entire comparison between these two medications

Researchers found that exposure to the medication was similar across all groups compared with people with normal liver function

Certain bacteria, including Akkermansia muciniphila, support GLP-1 secretion by improving gut barrier function, reducing inflammation, and promoting the production of short-chain fatty acids