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35 Therefore, dietary recommendations for protein should always be strongly paired with advice to engage in regular resistance training (typically suggested 2-4 times per week) to optimize body compositionmaximizing fat loss while minimizing muscle loss

In the ARC, GLP-1 has a dual effect: it activates pro-opiomelanocortin (POMC) neurons while inhibiting neuropeptide Y/agouti-related protein (NPY/AgRP) neurons

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