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Supplementation of cystine restored mTORC1 signaling and treatment with rapamycin (a specific mTORC1 inhibitor) abolished the induction, providing evidence for the direct role of mTORC1 in the phosphorylation of p70S6K (T389) and S6 (S235/236)

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2022;7(2), e10525

[1] Skin lightening or bleaching refers to the cosmetic practice of applying depigmenting agents not as treatment for hyperpigmentation but with the deliberate aim of achieving a lighter skin colour