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While baseline ROS levels can support cancer cell survival, excessive ROS can damage cellular components and paradoxically fuel tumor development (123, 124)
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FASEB J (2010) 24(4):102334
Importantly, these methods also allow for the integration of OMICs data such as transcriptomics, proteomics, and metabolomics to reconstruct metabolic models that more accurately reflect the metabolic state of cells in a given condition, so-called context-specific metabolic models 18