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Combination therapy with azacitidine and trametinib was well-tolerated except for an intermittent eczematous skin rash (thought to be secondary to trametinib), temporarily reduced longitudinal growth (possibly related to frequent shunt complications and streptococcus pneumoniae meningitis during this time) and intermittent nausea/vomiting
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma
Tschoepe D
N.1993Cloning and expression of human liver dehydroepiandrosterone sulphotransferase.289No
Therefore, the development of an oral delivery strategy for peptide GLP-1R agonists is expected to reduce these adverse effects and improve patient compliance and quality of life (Borner et al., 2020
