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The compound never made it through formal drug development

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Beyond its autophagic role, spermidine also influences other cellular processes, including mitophagy, which is the selective removal of damaged mitochondria

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GLP-1RAs, which are approved to treat type 2 diabetes, obesity, and obstructive sleep apnea, are now being investigated for their effects on processes involving appetite and satiety, reward processing, stress regulation, cognition, and neuroinflammation

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KPV (Dalmasso et al., 2008): Alpha-MSH fragment that directly suppresses NF-kB the master inflammatory switch

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