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People with a higher BMI, a prolonged history of weight cycling, or metabolic conditions such as type 2 diabetes or insulin resistance are generally considered better candidates for sustained treatment

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As of 2024, the FDA finalized action placing ipamorelin on the list of bulk drug substances that cannot be used in compounding under Section 503A (traditional pharmacies) or 503B (outsourcing facilities)

In short GLP-1s can subtly dehydrate you without you realizing it