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When SGLT-2is were added to metformin therapy, an increase rather than a reduction in DR risk was observed [89], likely because metformin itself provides more than twice the estimated protective effect - approximately a 56% risk reduction compared with 25% for SGLT-2is (Figure 7)

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While standard L-carnitine is highly effective at facilitating physical energy production in muscle tissues, its ability to reach the central nervous system is notoriously limited

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But as we age, levels dropleading to fatigue, brain fog, and dull skin