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(21(2)):155-64 doi:10.12809/hkmj144383

While retatrutide shows lower potency at human GLP-1 and glucagon receptors compared to natural ligands, it demonstrates higher potency at the GIP receptor by a factor of nearly 9x, and the combined effect is what drives the superior outcomes

Both peptides have a strong safety profile when used under medical supervision with proper dosing and regular lab monitoring