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This was not a significant finding in the Phase 2 trial, making it a genuinely new safety signal
Most research focuses on its ability to support the skins regenerative processes, reduce inflammation, and remodel the extracellular matrix, which are all beneficial for post-acne recovery and overall skin health
SURMOUNT-1 reported nausea in 25%, vomiting in 10%, diarrhea in 18%, constipation in 11%
Wysock was concerned about making the switch, fearing that the compounded version would cause unfamiliar side effects, but it was worth it to me to try. Its not a normal situation that a blockbuster drug immediately goes on shortage and meets criteria for compounding pharmacies to compound it
Key Takeaways: Both options address insulin resistance, a core issue in PCOS
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