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Beyond their metabolic effects, GLP-1 RAs have demonstrated cardiovascular and renal benefits in large outcome trials, including reductions in major adverse cardiovascular events (MACE) and attenuation of albuminuria progression ( Table 1 , renal eligibility criteria across landmark GLP-1 RA cardiovascular and kidney outcome trials consistently excluded dialysis-dependent patients, resulting in a persistent lack of randomized evidence in this high-risk population
adaptation to starch-rich diets 6
Mounjaro is a licensed medicine containing tirzepatide
Some doctors may use GLP-1 medicines off-label, but approval and availability can change over time, so confirm the current status with your doctor and pharmacy
Very common side effects include [4, 5]: Liraglutide: Nausea Diarrhoea Constipation Headache Fatigue Semaglutide: Nausea Vomiting Constipation Abdominal pain Headache Fatigue Serious side effects of both medications may include severe abdominal pain which could be a sign of pancreatitis, gallbladder problems, or very low blood sugar (especially in people also taking diabetes medications)
