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Srensen G, Caine SB, Thomsen M
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Rats given methotrexate have shown evidence of diminished nutritional status of choline and greater drug adverse reactions due to liver dysfunction (12, 124)
Wang et al., 2023) and the secretion of proinflammatory mediators by accumulating senescent cells, which may lead to tissue infiltration of immune cells, chronic inflammation, and tissue damage (Islam et al., 2023
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