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Yet, riboflavin supplementation is increasingly explored in specific clinical settings, for example in case of preeclampsia 24 , anemia during pregnancy 25 , Parkinsons disease and migraine 26 , and female 27 , and postpartum depression 28 , as further discussed below

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Methods Ethics statement The Ethics Committee (IRB) of Oilfield General Hospital (Daqing City, Heilong Jiang Province, China) recognizes that this systematic review and meta-analysis of de-identified, publicly available data does not constitute human subjects research as defined by relevant national regulations, and therefore does not require Ethics Committee review

Future research will probably include more patients with combined therapy, which will help to elucidate the timing and sequence of how these medications should be combined

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