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Abrupt withdrawal has been linked to severe complications, including Posterior Reversible Encephalopathy Syndrome (PRES), hypertensive encephalopathy, stroke, and death (Thorpe et al., 2025)

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Specifically, the label states these medications should be used in combination with a reduced calorie diet and increased physical activity. HaVy Ngo-Hamilton, PharmD, pharmacist and clinical consultant for BuzzRx, states that the amount of diet and exercise will vary among users, leading to various degrees of weight loss

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