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But that entire safety dataset is three small animal studies with no formal toxicology arm, no dose escalation, no repeat dosing, no long-term follow-up, and nothing in humans

Those are not the same as an approved patient label

Health Benefits Comparison Both L-citrulline and L-arginine offer impressive health benefits, but their differing bioavailability and metabolic pathways create certain distinctions in their effects

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Altered absorption efficiency therefore represents an additional constraint-sensitive module