however, there was no change in the result, suggesting that this molecule does not bind PV2, despite the reported EC 50 of 27 nM against PV1 28
Novel compounds and therapeutic approaches exhibit restricted clinical efficacy attributable to factors such as short half-life, in vivo stability, and challenges associated with blood-brain barrier penetration, among others (177)
The key question is not which sounds more advanced. It is which one has stronger human evidence
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Bedaiwy, M.A., Al Inany, A.R., Falcone, T