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Taken together, these results show a significant inactivation of both Trx1 and Trx2 in Saos-2 and Saos-2-His-273 cells upon treatment with APR-246, through MQ binding to free thiols

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However, its important to keep one foot on the ground: while results have been encouraging, scientists and dermatologists agree that larger, longer-term studies are still needed to truly understand the long-term safety and effectiveness of peptide therapy