Abbreviations BP: Blood pressure CI: Confidence interval CIMT: Carotid intima-media thickness eGFR: Estimated glomerular filtration rate HbA1C: Hemoglobin A1c HDL: High-density lipoprotein cholesterol ICA: Internal carotid artery L-C: L-carnitine LDL-C: Low-density lipoprotein cholesterol Lp(a): Lipoprotein (a) MetS: Metabolic syndrome MI: Myocardial infarction MPH: Maximum plaque height NSAIDs: Nonsteroidal anti-inflammatory drugs SAEs: Serious adverse events TMAO: Metabolites such as trimethylamine oxidase TPA: Total plaque area TPV: Total plaque volume WC: Waist circumference References Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr, et al
Compounded semaglutide and tirzepatide are not FDA-approved medications
This is observational data association, not proven causation
They are often injectable medications that are combined with other treatmentssuch as diet, exercise, medication, or bariatric surgeryto promote weight loss and manage blood sugar levels
Tight glucose management reduces the risk of congenital anomalies and other complications