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Initially, orally administered vitamin B12 is tightly bound to the protein Haptocorrin (HC), encoded by the TCN1 gene, which is released into saliva to protect it from active, harmful factors, such as HCl, in the stomach and intestines [98, 99]

Serum (the liquid portion of blood) is commonly used to test vitamin B12 and folate

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In the UK, hydroxocobalamin injections are prescription-only medicines and should only be administered when clinically indicated

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