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[5] [6] Early-phase clinical trials including a Phase 2 trial published in the New England Journal of Medicine (2023) have reported significant reductions in body weight and improvements in metabolic markers, though this evidence remains preliminary and is not sufficient to establish a clinical dosing or reconstitution standard

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Future investigations into the effects of GLP-1 RAs in neurological and mental disorders should also endeavour to ascertain CNS target engagements

Stopping GLP-1s leads to weight regain and inflammation, unless healthy habits support those changes. Why do insurance companies often deny coverage for GLP-1 medications