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Malabsorption disorders and IBD : Crohns, celiac, and other gastrointestinal disorders can cause damage to the intestinal lining, preventing the body from absorbing B12 and other nutrients effectively

There are no controlled trials of microinfusion-delivered peptides and growth factors in pregnancy, and the regulatory and clinical default in the absence of safety data is non-intervention

Every vial top is a potential entry point for contamination once it has been punctured

And for patient populations for whom daily IV administration is a significant lifestyle disruption, oral supplementation can be a valuable addition to an individuals daily supplement regimen

Their combined use in laboratory settings is of interest due to their potentially complementary mechanisms in supporting repair processes