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The Phase 2 trial data showed nausea in roughly 28% of patients at the 12mg dose, diarrhea in 24%, vomiting in 17%, and constipation in 11%
AOD9604 and Energy Balance Research In obese ob/ob and lean C57BL/6J mice treated for 14 days via mini-osmotic pumps, AOD9604 significantly reduced body weight gain in obese mice, associated with increased in vivo fat oxidation and increased plasma glycerol levels as an index of enhanced lipolysis without the hyperglycaemia or reduced insulin secretion associated with intact hGH treatment
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Research context Research context Intended for non-clinical studies, GHK-Cu is used to probe copper-dependent peptide signaling, matrix metalloproteinase regulation, collagen and elastin expression, cell migration and proliferation, antioxidant and anti-inflammatory responses, and mechanistic combination studies with growth factors or metabolic agents
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