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Phase 2 trial data Tirzepatide Phase 3 trials (SURPASS and SURMOUNT programs) demonstrated weight loss of 15 to 22.5% body weight depending on dose and study population
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Methods 25 , 402408, doi: 10.1006/meth.2001.1262 (2001)
To best visualize the effects of PAG, data was normalized to untreated hepatocytes in each group and therefore PAG-untreated values are 1.0
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