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The LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) trial was a pivotal milestone as it showed the cardiovascular benefits of liraglutide in patients with T2D and high cardiovascular risk
By not doing so, doctors also couldnt warn their patients of the potential exacerbation of their gastroparesis if they already were suffering from it so that they could make an informed decision about whether to take the drug By 2022, researchers additionally tied gallbladder issues to this class of drugs, which opened the door to the first round of lawsuits against manufacturers
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