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Moreover, these claims require caution because: As a result, animal body composition findings may not translate directly to humans

The higher the energy needs (higher metabolism, exercise, stress, etc.), the harder the mitochondria have to work and the more free radicals they produce

This doesn't mean they're dangerous, but it means the full risk profile isn't established with the certainty that approved drugs provide

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Combining cagrilintide peptide with semaglutide weight loss therapy may increase these effects initially, but tolerability usually improves over time