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Although these agents offer transformative therapeutic potential, their optimal use requires individualized care, careful patient selection, and ongoing safety surveillance

Thymoquinone (TMQ) has strong anti-psoriatic efficacy, but its hydrophobicity, low water solubility, and light and pH sensitivity limit its transport to the target site

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Tsilou ET, Rubin BI, Reed G, Caruso RC, Iwata F, Balog J, Gahl WA, Kaiser-Kupfer MI (2006) Nephropathic cystinosis: posterior segment manifestations and effects of cysteamine therapy