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These targeted accumulation patterns align with the body's natural glutathione distribution, suggesting that the acetyl modification preserves the molecule's inherent tissue selectivity

However, research indicates that its therapeutic effect increases if taken via the orobuccal route (placing the medicine in your mouth and letting it dissolve inside your cheeks)

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Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12

10.2174/156720112803529828 33 GreenM.LoewensteinP