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It cites STEP 1, STEP 2 and STEP 3 for semaglutide and SURMOUNT 1-4 for tirzepatide as enrolling people across varying activity levels, with average weight loss of 5-10% without structured fitness
They discovered that semaglutide treatment improved body composition by reducing excess body fat, notably abdominal fat, and increasing the proportion of lean body mass, or weight that is not body fat
Semaglutide, StatPearls Publishing, 2024
However, what one eats and how much one eats will likely affect the efficacy and tolerability of the medication