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Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial

Abstract Oxidative and carbonyl stresses (COS), which damage brain cells through the accumulation of toxic reactive carbonyl species (RCS), are key players in the etiology of Alzheimers disease (AD)

Thats important because it wasnt clear until now that these patients would see heart benefits, says Tiffany Powell-Wiley, a cardiologist and epidemiologist at the National Heart, Lung and Blood Institute in Bethesda

In the SCALE Maintenance trial itself, there was only one death due to heart failure, and that death occurred in the placebo group