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It helps to prevent damage to cells caused by free radicals, which can lead to aging, disease, and skin damage

In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway (Yao et al., 2024)

This is important for control retinas, but it is even more crucial for retinas with RP where the progressive loss of rods leads to increased oxygen tension and thereby exacerbated photo-oxidation

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& Nuss, J