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La molcula no presenta homologa estructural con factores de crecimiento clsicos (VEGF, FGF, IGF-1), pero modula la expresin y actividad de mltiples sistemas trficos endgenos , posicionndola como agente pleiotrpico de proteccin y regeneracin tisular en investigacin experimental
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It is critical to recall that all of this data comes from preclinical models (rodent, porcine, in vitro) and limited case studies
273 , C1378C1385 (1997)
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