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But there has been concern that they induce loss of muscle and other components of lean body mass along with fat
Side Effects & Safety Nausea 44% in STEP trials, most common side effect, dose-dependent Diarrhea 30% in trials Vomiting 24% in trials Constipation 24% in trials Stomach pain 20% in trials Pancreatitis rare but documented
[7] [9] Contraindications and precautions for GLP-1 receptor agonists, as detailed in UK Summaries of Product Characteristics (SmPCs), include: Contraindications: Pregnancy
4 GLP-1 Theories on Regeneration and Proliferation The exact mechanism of GLP-1 binding to GLP-1 receptor coupled with beta cell release of insulin is unknown
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