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Symptoms of gallbladder problems include right upper abdominal pain, especially after fatty meals

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TRPM8 is expressed on trigeminal sensory neurons involved in migraine pain signaling and represents a biological pathway distinct from those targeted by existing migraine therapies, including calcitonin gene-related peptide (CGRP) receptor antagonists

She also suggests speaking to a behavioral health provider beforehand to screen for issues that could exacerbate mental health problems while on the medication, such as eating disorders or unmanaged mental health concerns