This is why some practitioners prefer it not just for multi-dose use but specifically because it's designed to remain chemically stable in a vial over an extended period
According to the Mayo Clinic, supplementing with B12 injections without having a deficiency will not induce weight loss, but is not likely to cause harm either
All peptide therapy requires physician supervision and comprehensive health assessment
[26] [27] [28] Hypoglycemia, arginine, [29] pramipexole, [30] ornithine, lysine, tryptophan, -Aminobutyric acid and propranolol by inhibiting somatostatin release [25] Deep sleep [31] Glucagon Sodium oxybate or -Hydroxybutyric acid Niacin as nicotinic acid (vitamin B 3 ) [32] Fasting [33] Insulin [34] Vigorous exercise [35] Inhibitors of GH secretion include: GHIH ( somatostatin ) from the periventricular nucleus [36] circulating concentrations of GH and IGF-1 (negative feedback on the pituitary and hypothalamus) [3] Hyperglycemia [25] Glucocorticoids [37] Dihydrotestosterone Phenothiazines In addition to control by endogenous and stimulus processes, a number of foreign compounds (xenobiotics such as drugs and endocrine disruptors) are known to influence GH secretion and function
If you have been taking oral B12 supplements without feeling any improvement, this may be why