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Weeks four through eight Most users who experienced initial injection site reactions notice significant improvement during this period
For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said
Higher investigational doses (25mg and 50mg) in the PIONEER PLUS trial showed weight reductions of approximately 10% body weight, approaching levels seen with injectable weight-loss medications
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However, the side effects, such as fatigue, dizziness, and a general sense of malaise, were challenging
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