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Phase 2 reported -24.2% body weight at 48 weeks at 12 mg, and Phase 3 TRIUMPH-4 reported up to -28.7% at 68 weeks at 12 mg

If severe fatigue persists past week 16, discuss with physician as this may indicate inadequate nutrition or other factors

They look unrecognizable. Not for the first time, my friends and I were having a conversation about GLP-1s, a type of medication that has become widely used for weight loss

10.1016/j.cell.2018.10.001 47 KalamkarS.AcharyaJ.Kolappurath MadathilA.GajjarV.DivateU.Karandikar-IyerS.et al (2022)

Slower Gastric Emptying: They slow down the rate at which food empties from your stomach, which helps you feel fuller for longer