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The peptide influences vasomotor tone through the Src-caveolin-1-eNOS pathway, affecting both vasoconstriction and vasodilation depending on baseline vascular state
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In addition to the similarity of certain metabolic signaling pathways such as the Wnt/-catenin pathway, Heregulin-HER3-HER2 signaling and the EGFR/PI3K/Akt pathway, brain metastatic cancer cells also share certain metabolic characteristics with neuronal cells (152)
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