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The following mild side effects are frequently reported: Injection site irritation (temporary) Headaches Flushed skin or warm skin Mild water retention or bloating Sleepiness or vivid dreams Unlike older GH-Releasing peptides, Ipamorelin does not raise cortisol or prolactin levels to a significant extent, making it one of the more gentle options available

Some people notice more energy throughout the day

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ODonnell M, Mente A, Rangarajan S, McQueen MJ, Wang X, Liu L, Yan H, Lee SF, Mony P, Devanath A, et al

This improves collateral circulation enhances myocardial perfusion and recovery after MI (Yu et al