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Weight loss medications should not be a stand-alone treatment but a part of comprehensive obesity care, also focusing on nutrition, physical activity, and mental health

In PIONEER 10, patients were instructed to take their tablet in the morning, fasted, with no more than approximately 120 mL of water, and then to wait at least 30 min before consuming any food, other beverage, or other oral medication [26]

The downstream release of these three factors, in response to GLP-1R activation, leads to glucose-dependent insulin release

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