It develops when the immune system overreacts, attacking intestinal tissue and triggering ulcers, pain, and bleeding
Nasal spray considerations: Typically lower bioavailability than injection, requiring somewhat higher doses Faster onset in some users due to direct CNS access More convenient and less intimidating for needle-averse individuals Requires properly calibrated spray bottles for accurate dosing Converting from injectable to nasal dosing is not straightforward
Blood clots in the vein of the legs (deep vein thrombosis, DVT) and lungs (pulmonary embolism, PE) have happened more often in people who are 50 years of age and older and with at least 1 heart disease (cardiovascular) risk factor taking a medicine in the class of medicines called JAK inhibitors by mouth
[46] Bettge K, Kahle M, Abd El Aziz MS, Meier JJ, Nauck MA
Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives