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High purity ensures that the observed biological effects arise from the intended peptide sequence rather than from truncated peptides, synthesis byproducts, or residual reagents
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Platelet glycoprotein IIb/IIIa inhibitors in percutaneous coronary intervention: focus on the pharmacokineticpharmacodynamic relationships of eptifibatide
The five high-resolution cryo-EM structures reported here, together with abundant structural and pharmacological data of monospecific peptides documented previously 4,25,27,30,40 , provide us an excellent opportunity to analyze the molecular basis of the superior clinical efficacy presented by multi-targeting agonists
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