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The threshold increase is precautionary
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You can decide which method to choose depending on which one is more comfortable for you
It is widely used to treat vitamin B12 deficiency and is typically administered by a healthcare professional following a consultation
Some community members are running this sequence deliberately: start with NAD+ precursors (NMN/NR) to raise the baseline pool, then add MOTS-C to put that pool to work, then layer in 5-Amino-1MQ to block the pathway that drains it
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