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Data show that up to two-thirds of patients with HFpEF have CAD or coronary microvascular dysfunction including ischaemia, which leads to disruption of LV diastolic and systolic function, development of fibrosis, increased myocardial stiffness and cardiac remodelling

Nitin Ranjan The skin-whitening market has become a billion-dollar industry worldwide, as lots of people are obsessed to get a fair complexion

Second, weight loss had not plateaued at 80 weeks: in a pre-specified extension involving 532 participants with a baseline BMI of 35 or above, those continuing to 104 weeks reached an average of 30.3 per cent

That matters even more on GLP-1, where the weight change often unfolds over many months rather than a few dramatic weeks

Several promising studies in animal models demonstrated a marked improvement in cognition