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Misguided drug advice for COVID-19
This direct transport of extracellular cystine does not take place in hepatocytes, where the reduction of cystine to cysteine occurs mainly in the outer cell membrane as a consequence of GSH efflux (11)
(2013) demonstrated, in a mouse model with deletion of INSR in the kidney tubule cells, that depending on the segment targeted with INSR deletion, there were different phenotypes further described
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