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In summary, the findings of impaired IGF-1 synthesis, together with modest elevation of GH-levels due to decreased renal clearance, and increased IGF plasma binding capacity, provides evidence of a multilevel, homeostatic failure in the GH-IGF-1 system in CKD, which has paved the way for studies proving the stimulatory growth effects of GH in short children with CKD [163]
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Potential Therapeutic Applications Research on the potential therapeutic applications of BPC-157 and GHK-Cu focuses on their ability to enhance tissue repair
Pain and Analgesic Potential Studies in rodent models suggest that GHK-Cu has analgesic effects, partly due to its ability to increase levels of natural pain-relieving amino acids such as L-lysine and L-arginine
