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While regulation of iron metabolism-related proteins or the use of iron chelators can reduce intracellular labile Fe 2+ levels and inhibit ferroptosis, current chelators lack tissue and cellular specificity and may interfere with neurophysiological functions, thereby limiting their clinical applicability

Mechanism-Based Inhibition of Human Steroid 5-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADPDihydrofinasteride, a Potent Bisubstrate Analog Inhibitor.J.Amer.Chem.Soc.1996,118, 2359-2365 78

Transmembrane glutathione cycling in growing Escherichia coli cells

A basic dose log should include: date, time, dose in mg, concentration of vial, units drawn, injection site, and any side effects noted