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Patients on GLP-1 therapy may experience orthostatic hypotension or symptomatic hypotension at any position
This effect moreover extended to alcohol-induced increases in dopamine metabolites 3,4-dihydroxyphenylacetic acid (DOPAC), 3-methoxytyramine (3-MT), and homovanillic acid (HVA), which tirzepatide similarly reduced ( Fig
2011;17(12):CR677-CR682
By improving overall metabolic health, reducing excess adiposity, and alleviating adipose tissue inflammation, tirzepatide could potentially mitigate upper airway collapsibility and ameliorate the underlying pathophysiological mechanisms of OSAS (27)
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