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Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial

Peak concentration arrives between 8 and 72 hours post-injection, with most users hitting Tmax around 24 to 48 hours

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They come from the stomach and gut slowing down

The Nde I restriction site upstream of torA was then removed by QuickChange mutagenesis (Agilent, Waldbronn, Germany) according to the manufacturers protocol using primers QC- Nde I-fw and QC- Nde I-rv (Supplementary table S3) resulting in the pPT plasmid