JAMA Psychiatry 2025;82:643-653
Harris-Pincus, who is also the author of "Everything Easy Pre-Diabetes Cookbook," told the publication that she suggests consumers look for "supplements that are third-party tested and verified." When asked if consumers should be cautious about Kourtney Kardashian's capsules, she said, "This supplement probably won't harm most people, except for their wallets." Harris-Pincus said it is important to consider "permanent diet and lifestyle changes," such as " eating fiber-rich foods that stimulate natural GLP-1 and help keep us full." The registered dietitian nutritionist said it's "unlikely" that a supplement will have a "more significant effect" than a high-protein and high-fiber diet.
Its stability depends on the metal staying coordinated to the tripeptide, which makes it sensitive to pH, since the deprotonated amide nitrogen that helps hold the copper is pH-dependent, and outright incompatible with two whole classes of common additive
Individual response, tolerance and treatment duration vary
If youre wondering about the variability between these results, its worth noting that the study populations differ